Critical care medicine · 2003
Successful treatment of Candida krusei infection with caspofungin acetate: a new antifungal agent.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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McGee William T, Tereso Gary J
Аннотация
OBJECTIVE: Systemic fungal infections have high mortality, and therapy is often toxic. Caspofungin acetate, a new antifungal agent with minimal toxicity, may provide a better alternative to typical therapy for Candida krusei.
DESIGN: Case report.
SETTING: Multidisciplinary intensive care unit (ICU) of a community teaching hospital.
PATIENT: A 22-yr-old male with acute lymphoblastic leukemia and Candida krusei fungemia failed therapy with fluconazole and amphotericin B.
INTERVENTIONS: Caspofungin acetate given intravenously as a 70-mg loading dose, followed up by 50 mg daily along with standard ICU care.
RESULTS: Survival without toxicity from therapy.
CONCLUSION: Efficacy of caspofungin acetate in a patient with life-threatening Candida Krusei infection.
DESIGN: Case report.
SETTING: Multidisciplinary intensive care unit (ICU) of a community teaching hospital.
PATIENT: A 22-yr-old male with acute lymphoblastic leukemia and Candida krusei fungemia failed therapy with fluconazole and amphotericin B.
INTERVENTIONS: Caspofungin acetate given intravenously as a 70-mg loading dose, followed up by 50 mg daily along with standard ICU care.
RESULTS: Survival without toxicity from therapy.
CONCLUSION: Efficacy of caspofungin acetate in a patient with life-threatening Candida Krusei infection.
Предметные рубрики MeSH
AdultAmphotericin BAnti-Bacterial AgentsAntifungal AgentsCandidaCandidiasisCaspofunginEchinocandinsFluconazoleFungemiaHumansInfusions, IntravenousLipopeptidesMaleNeutropeniaOpportunistic InfectionsPeptidesPeptides, CyclicPleural EffusionPrecursor Cell Lymphoblastic Leukemia-LymphomaTomography, X-Ray ComputedTreatment Outcome