American journal of cardiovascular drugs : drugs, devices, and other interventions · 2020
Amiodarone: A Comprehensive Guide for Clinicians.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Hamilton David, Nandkeolyar Shuktika, Lan Howard, Desai Pooja, Evans Jonathan, Hauschild Christopher, Choksi Dimpa, Abudayyeh Islam, Contractor Tahmeed, Hilliard Anthony
Аннотация
Amiodarone is an effective antiarrhythmic medication frequently used in practice for both ventricular and atrial arrhythmias. Though classified as a class III antiarrhythmic, it affects all phases of the cardiac action potential. However, the drug has several side effects, including thyroid abnormalities, pulmonary fibrosis, and transaminitis, for which routine monitoring is recommended. It also interacts with several medications, such as warfarin, simvastatin, and atorvastatin, and many HIV antiretroviral medications. Given the common use of this medication in medical practice, it is vital that clinicians understand the indications, contraindications, dosing, side effects, and interactions of this medication. A thorough understanding of these topics is essential for clinicians to ensure safe and effective use of amiodarone.