Current protein & peptide science · 2019
In Silico Studies against Viral Sexually Transmitted Diseases.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Monteiro Alex F M, de Oliveira Viana Jessika, Muratov Engene, Scotti Marcus T, Scotti Luciana
Аннотация
Sexually Transmitted Diseases (STDs) refer to a variety of clinical syndromes and infections caused by pathogens that can be acquired and transmitted through sexual activity. Among STDs widely reported in the literature, viral sexual diseases have been increasing in a number of cases globally. This emphasizes the need for prevention and treatment. Among the methods widely used in drug planning are Computer-Aided Drug Design (CADD) studies and molecular docking which have the objective of investigating molecular interactions between two molecules to better understand the three -dimensional structural characteristics of the compounds. This review will discuss molecular docking studies applied to viral STDs, such as Ebola virus, Herpes virus and HIV, and reveal promising new drug candidates with high levels of specificity to their respective targets.