Journal of Asian natural products research · 2024
Two new glycosides and a new flavone from Gerbera delavayi.
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Wen Yu-Shuang, Jiang Li, Wang Yang, Xu Ying-Jie, Liu Chun-Hua, Huang Yong, Ma Xue, Li Yong-Jun
Аннотация
Three new compounds, including two glycosides, named gerbelavinsides E/G (1/2), and a flavone, named gerbelavin G (3), were isolated from 50% ethanol extract of Gerbera delavayi. Their structures were elucidated based on HR-ESI-MS, IR, UV and NMR spectral data, and the absolute configurations of 1 and 3 were determined by ECD spectra. Three compounds were tested for their inhibition effect against LPS-induced NO production in RAW 264.7 cells. They exhibited different degrees of inhibition activities with rates of 40.55 ± 1.65%, 70.13 ± 0.55%, 56.74 ± 1.15%, respectively.