Critical care medicine · 2004
Ventilatory management of acute respiratory distress syndrome: a consensus of two.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Marini John J, Gattinoni Luciano
Аннотация
OBJECTIVE: To synthesize the emerging body of experimental, observational, and clinical trial data into a practical guideline for safe and effective ventilatory management of acute respiratory distress syndrome.
DATA SOURCES: Relevant, peer-reviewed, scientific literature and personal observations from clinical practice.
STUDY SELECTION: Relevant experimental studies and high-impact observational and clinical trials of acute respiratory distress syndrome management.
DATA EXTRACTION: Detailed review of information contained in published scientific work.
DATA SYNTHESIS: Interactive discussions between the authors that culminated in our consensus view of appropriate management.
CONCLUSIONS: Prevention of ventilator-induced lung injury while accomplishing the essential life-supporting roles of mechanical ventilation is a complex undertaking that requires application of principles founded on a broad experimental and clinical database and on the results of well-executed clinical trials. At the bedside, execution of an effective lung-protective ventilation strategy remains an empirical process best guided by integrated physiology and a readiness to revise the management approach depending on the individual's response.
DATA SOURCES: Relevant, peer-reviewed, scientific literature and personal observations from clinical practice.
STUDY SELECTION: Relevant experimental studies and high-impact observational and clinical trials of acute respiratory distress syndrome management.
DATA EXTRACTION: Detailed review of information contained in published scientific work.
DATA SYNTHESIS: Interactive discussions between the authors that culminated in our consensus view of appropriate management.
CONCLUSIONS: Prevention of ventilator-induced lung injury while accomplishing the essential life-supporting roles of mechanical ventilation is a complex undertaking that requires application of principles founded on a broad experimental and clinical database and on the results of well-executed clinical trials. At the bedside, execution of an effective lung-protective ventilation strategy remains an empirical process best guided by integrated physiology and a readiness to revise the management approach depending on the individual's response.