Accuracy or inaccuracy of spleen mass measurements from radionuclide images.

In a retrospective study, scintigraphic spleen size was compared with actual spleen weight. Using the formula W = pi/7 h (h2 + 3ab), the normal weight was calculated too large and splenic enlargement was calculated too small. Other scintigraphic parameters seem to be just as unreliable. We suggest to judge scintigraphic spleen mass as normal and only be enlarged in obvious situations.