Early human development · 2014
Infants of opioid-dependent mothers: neurodevelopment at six months.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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McGlone Laura, Mactier Helen
Аннотация
OBJECTIVE: The aim of this study is to describe infant neurodevelopment in 81 infants of methadone-prescribed opioid-dependent mothers.
METHODS: Griffith MD scores at six months.
RESULTS: Scores were lower in all domains compared to controls (p<0.001). Poly-drug exposed infants and those treated for neonatal abstinence syndrome performed significantly poorer (p=0.002 and p=0.008 respectively).
CONCLUSIONS: Infants of methadone-maintained opioid-dependent mothers show poorer neurodevelopment at six months of age than non-drug exposed comparison infants. Developmental difficulties are confounded by delayed visual development.
PRACTICE IMPLICATIONS: These highly vulnerable children merit close surveillance throughout infancy.
SUMMARY: Griffith MD scores at six months in 81 infants born to methadone-prescribed opioid-dependent mothers were lower in all domains compared to controls (p<0.001). Poly-drug exposed infants and those treated for neonatal abstinence syndrome performed significantly poorer (p=0.002 and p=0.008 respectively). Co-existing visual problems were common.
METHODS: Griffith MD scores at six months.
RESULTS: Scores were lower in all domains compared to controls (p<0.001). Poly-drug exposed infants and those treated for neonatal abstinence syndrome performed significantly poorer (p=0.002 and p=0.008 respectively).
CONCLUSIONS: Infants of methadone-maintained opioid-dependent mothers show poorer neurodevelopment at six months of age than non-drug exposed comparison infants. Developmental difficulties are confounded by delayed visual development.
PRACTICE IMPLICATIONS: These highly vulnerable children merit close surveillance throughout infancy.
SUMMARY: Griffith MD scores at six months in 81 infants born to methadone-prescribed opioid-dependent mothers were lower in all domains compared to controls (p<0.001). Poly-drug exposed infants and those treated for neonatal abstinence syndrome performed significantly poorer (p=0.002 and p=0.008 respectively). Co-existing visual problems were common.