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Войти в исследования American journal of ophthalmology · 2001
Keratitis caused by Candida glabrata in a patient with chronic granulomatous disease.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Djalilian A R, Smith J A, Walsh T J, Malech H L, Robinson M R
Аннотация
PURPOSE: To report an unusual ocular presentation of Candida glabrata in a patient with chronic granulomatous disease.
METHODS: Interventional case report. A 15-year-old boy with chronic granulomatous disease presented with bilateral limbal infiltrates. He had been receiving broad-spectrum systemic antibiotics for recurrent liver abscesses. The keratitis did not respond to antibiotics and did not resolve after a course of topical steroids.
RESULTS: Corneal cultures revealed Candida glabrata. The same species was simultaneously isolated from the surgical drainage of the liver abscesses. The ocular and hepatic findings resolved on intravenous amphotericin B.
CONCLUSION: Candida glabrata has recently emerged as an important nosocomial pathogen. It may present as a limbal keratitis in the setting of systemic infection.
METHODS: Interventional case report. A 15-year-old boy with chronic granulomatous disease presented with bilateral limbal infiltrates. He had been receiving broad-spectrum systemic antibiotics for recurrent liver abscesses. The keratitis did not respond to antibiotics and did not resolve after a course of topical steroids.
RESULTS: Corneal cultures revealed Candida glabrata. The same species was simultaneously isolated from the surgical drainage of the liver abscesses. The ocular and hepatic findings resolved on intravenous amphotericin B.
CONCLUSION: Candida glabrata has recently emerged as an important nosocomial pathogen. It may present as a limbal keratitis in the setting of systemic infection.