National prevalence and incidence of benign prostatic hyperplasia/lower urinary tract symptoms and validated risk factors pattern.

BACKGROUND

To date, limited research has been conducted within China to elucidate the national prevalence and incidence rates of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS). Additionally, there is a scarcity of studies that have systematically investigated the reliable risk factor patterns associated with the development of BPH/LUTS among the Chinese population.

METHODS

The study was in both cross-sectional and prospective cohort study design. The participants were derived from the China Health and Retirement Longitudinal Study (CHARLS). National prevalence and incidence of BPH/LUTS, average onset age of BPH/LUTS, medication rate of BPH/LUTS, and validated risk factors pattern of BPH/LUTS in the Chinese population were investigated.

RESULTS

The overall prevalence and annual incidence of BPH/LUTS were 11.10% and 2.23%. In China, the male population affected by BPH/LUTS typically presented at an average age of 55-65 years. However, the medication rate was merely more than 30%. After conducting univariate and multivariate logistic regression analysis in both cross-sectional and prospective cohort study designs, we observed that dyslipidemia was the most stable risk factor of BPH/LUTS occurrence in three adjusted models (OR [95% CI]: 2.41 [1.37-4.25]; 2.05 [1.10-3.81] and 2.40 [1.19-4.84], respectively).

CONCLUSIONS

This is the first study to delineate the prevalence and incidence of BPH/LUTS in Chinese, at the national level. The study reminded us that it was dyslipidemia rather than other chronic diseases or bad habits that posed a detrimental influence on BPH/LUTS occurrence in Chinese. Our data would facilitate the disease's early screening and medical policy formulation.