[Development of antibiotherapy at the General Hospital Center R Ballanger of Aulnay-sous-Bois between 1978 and 1986: comparison of 2 prevalence surveys].

Two investigations of the prevalence of antibiotherapy and pathology due to infections have been conducted in 1978 and 1986 in a General Hospital (650 beds). In the first investigation, 29%, and, in the second one, 20% of hospitalized patients received a curative antibiotherapy. Among these patients, microbiology tests scored positive in 44% of cases in the first investigation and in 36% of cases in the second one. In the last inquiry, it was found that: the prescription was adapted to the infection in 95% of cases; the choice of antibiotic was adequate in 78% of curative treatments. Preventive antibiotherapy accounts for 30% of treatments in both investigations. In the second investigation, the prescription was adequate in 97% of cases and the length of treatment was less than 72 hours in 53% of cases. The frequency of Gram-positive cocci infections was increased while Gram-negative bacilli infections were reduced. Between the two investigations, antibiotic treatments have changed. Most noticeably, there is an increase in the number of prescriptions of macrolides, cephalosporins, nitro-imidazole derivatives and a reduction of tetracyclines, urinary antiseptics, quinolones of the 1st generation, sulfamides and penicillins. However, penicillins remain the most commonly used antibiotics family.