The American journal of tropical medicine and hygiene · 2012
Modifiable risk factors for West Nile virus infection during an outbreak--Arizona, 2010.
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Gibney Katherine B, Colborn James, Baty Steven, Bunko Patterson Andrean M, Sylvester Tammy, Briggs Graham, Stewart Tasha, Levy Craig, Komatsu Ken, MacMillan Katherine, Delorey Mark J, Mutebi John-Paul, Fischer Marc, Staples J Erin
Аннотация
West Nile virus (WNV) is the leading cause of mosquito-borne disease in the United States; however, risk factors for infection are poorly defined. We performed a case-control study to identify modifiable risk factors for WNV infection. Case-patients (N = 49) had laboratory evidence of recent WNV infection, whereas control-subjects (N = 74) had negative WNV serology. We interviewed participants, surveyed households, and assessed environmental data. WNV infection was associated with living in or near Water District X within Gilbert Township (adjusted odds ratio [aOR] 5.2; 95% confidence interval [95% CI] = 1.5-18.1), having water-holding containers in their yard (aOR 5.0; 95% CI = 1.5-17.3), and not working or attending school outside the home (aOR 2.4; 95% CI = 1.1-5.5). During this outbreak, WNV infection was likely primarily acquired peri-domestically with increased risk associated with potential mosquito larval habitats around the home and neighborhood.