Fertility and sterility · 2007
Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener or immotile cilia syndrome.
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Kaushal Manila, Baxi Asha
Аннотация
OBJECTIVE: To describe a case of intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndrome and to discuss the role of micromanipulation in the treatment of these patients.
DESIGN: Case report.
SETTING: Private infertility clinic and assisted reproduction unit.
PATIENT(S): Couple with male factor infertility due to Kartagener's/immotile cilia syndrome.
INTERVENTION(S): The patient's partner underwent ICSI with testicular sperm.
MAIN OUTCOME MEASURE(S): Semen characteristics, sperm viability, fertilization and cleavage rate, pregnancy, and birth after ICSI.
RESULT(S): With testicular sperm, the two pronuclear fertilization rates were 53%. ICSI was successful in the first cycle. The uncomplicated pregnancy resulted in the birth of two healthy children, male/female twins.
CONCLUSION(S): With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener or immotile cilia syndrome is possible with nonprogressive motile sperm resulting in clinically healthy offsprings.
DESIGN: Case report.
SETTING: Private infertility clinic and assisted reproduction unit.
PATIENT(S): Couple with male factor infertility due to Kartagener's/immotile cilia syndrome.
INTERVENTION(S): The patient's partner underwent ICSI with testicular sperm.
MAIN OUTCOME MEASURE(S): Semen characteristics, sperm viability, fertilization and cleavage rate, pregnancy, and birth after ICSI.
RESULT(S): With testicular sperm, the two pronuclear fertilization rates were 53%. ICSI was successful in the first cycle. The uncomplicated pregnancy resulted in the birth of two healthy children, male/female twins.
CONCLUSION(S): With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener or immotile cilia syndrome is possible with nonprogressive motile sperm resulting in clinically healthy offsprings.