Alport's syndrome: case report and review of ocular manifestations.

A 66-year-old man with the classic signs of Alport's syndrome--progressive hemorrhagic nephropathy and sensorineural deafness--plus bilateral anterior lenticonus, anterior and posterior subcapsular cataracts, and scattered lens opacities is presented. Bilateral anterior leniconus is rarely seen in patients without the syndrome. The syndrome is usually fatal in males by the second or third decade of life. This patient is of interest because of his advanced age. We believe this patient is the oldest living man with the classical lesions known as Alport's syndrome.