Comparison of Carbon Dioxide Laser and Surgical Excision for the Treatment of Eyelid Margin Benign Tumors: A Prospective, Randomized, and Single-blind Study.

OBJECTIVES

This study aims to compare the safety and efficacy between carbon dioxide (CO 2 ) laser excision and surgical excision for the treatment of eyelid margin benign tumors.

METHODS

In this single-center, prospective, randomized, and single-blind study, 32 patients diagnosed with eyelid margin benign tumors were enrolled from February 2019 to February 2020 and randomly divided into 2 groups. The sexes, ages, tumor size (length×width), scar, procedure time, physicians' assessment score, patients' satisfaction score, and complications were recorded. Histologic analyses were obtained in all patients.

RESULTS

No significant difference in baseline data (sexes, ages, and tumor size) was found between the 2 groups. The mean scar length at 1-week post-treatment in the CO 2 laser excision group was significantly shorter than surgical excision group (0.3±0.1 versus 0.5±0.1 cm, P <0.05), and procedure time in CO 2 laser excision group was significantly shorter than surgical excision group (5.8±1.5 versus 26.7±6.4 min, P <0.05). There was no statistically significant difference in the physicians' assessment score and patients' satisfaction score between the 2 groups. During the follow-up period, no severe complications were observed.

CONCLUSIONS

Compared with surgical excision, CO 2 laser excision was a rapid procedure and associated with favorable cosmetic outcomes.