[Characteristics of a cell-culture infection with the tick-borne encephalitis virus with periodic replacement of the culture medium].

The following features were revealed in pig embryo kidney cell cultures infected with tick-borne encephalitis (TBE) virus in which the maintenance medium was changed periodically: more rapid accumulation of TBE virus-specific proteins, active proliferation of spherical vesicular structures and membrane elements of the endoplasmic reticulum, transformation of the latter into regularly arrayed complexes, a statistically significant increase in the yield of the infectious virus.