Fertility and sterility · 2000
Successful induction of ovulation using highly purified follicle-stimulating hormone in a woman with Kallmann's syndrome.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Battaglia C, Salvatori M, Regnani G, Giulini S, Primavera M R, Volpe A
Аннотация
OBJECTIVE: To describe a woman with Kallmann's syndrome who was treated successfully with highly purified FSH to achieve ovulation induction and pregnancy.
DESIGN: Case report.
SETTING: University hospital.
PATIENT(S): A 32-year-old woman with Kallmann's syndrome who had been treated with oral contraceptives to prime secondary sex characteristics and genital organs since the age of 16 years.
INTERVENTION(S): Highly purified FSH was administered intramuscularly for a total dose of 3,825 IU.
MAIN OUTCOME MEASURE(S): Follicle number and diameter.
RESULT(S): Three follicles with a diameter of > 1.7 cm and an endometrial thickness of 8 mm were observed. A clinical pregnancy, which subsequently was spontaneously aborted, was obtained.
CONCLUSION(S): In primed patients with Kallmann's syndrome, highly purified FSH may be a useful alternative to pulsatile GnRH or menopausal gonadotropins to achieve ovulation induction and pregnancy.
DESIGN: Case report.
SETTING: University hospital.
PATIENT(S): A 32-year-old woman with Kallmann's syndrome who had been treated with oral contraceptives to prime secondary sex characteristics and genital organs since the age of 16 years.
INTERVENTION(S): Highly purified FSH was administered intramuscularly for a total dose of 3,825 IU.
MAIN OUTCOME MEASURE(S): Follicle number and diameter.
RESULT(S): Three follicles with a diameter of > 1.7 cm and an endometrial thickness of 8 mm were observed. A clinical pregnancy, which subsequently was spontaneously aborted, was obtained.
CONCLUSION(S): In primed patients with Kallmann's syndrome, highly purified FSH may be a useful alternative to pulsatile GnRH or menopausal gonadotropins to achieve ovulation induction and pregnancy.