The Annals of pharmacotherapy · 1994
Close clinical observation minimizes the complications of beta-blocker withdrawal.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Eisele G, Gilmore L L, Blanchard E B
Аннотация
OBJECTIVE: To determine whether beta-blocker withdrawal under close medical supervision poses undue risks.
DESIGN: Retrospective case review. Data extracted from previous study.
SUBJECTS: 114 hypertensive subjects tapered from beta-blocker therapy. Subjects were a subset of patients originally studied for blood pressure medication withdrawal and biofeedback training.
MAIN OUTCOME MEASURES: Frequency of symptoms and adverse effects reported by subjects during medication taper to the study nurse.
RESULTS: Symptoms were no more likely to occur with beta-blocker withdrawal than with withdrawal of other types of antihypertensive medications. Most adverse effects were classified as minor. Two subjects experienced major symptoms. One subject required reinstitution of beta-blockers for palpitations, and another exhibited angina upon beta-blocker withdrawal.
CONCLUSIONS: In well-screened patients under careful monitoring, withdrawal from beta-blockers appears to present a small, manageable risk.
DESIGN: Retrospective case review. Data extracted from previous study.
SUBJECTS: 114 hypertensive subjects tapered from beta-blocker therapy. Subjects were a subset of patients originally studied for blood pressure medication withdrawal and biofeedback training.
MAIN OUTCOME MEASURES: Frequency of symptoms and adverse effects reported by subjects during medication taper to the study nurse.
RESULTS: Symptoms were no more likely to occur with beta-blocker withdrawal than with withdrawal of other types of antihypertensive medications. Most adverse effects were classified as minor. Two subjects experienced major symptoms. One subject required reinstitution of beta-blockers for palpitations, and another exhibited angina upon beta-blocker withdrawal.
CONCLUSIONS: In well-screened patients under careful monitoring, withdrawal from beta-blockers appears to present a small, manageable risk.