[Pathogenesis of progressive forms of tick-borne encephalitis].

An analysis of the pathogenesis of progressive forms of tick-borne encephalitis based on observations of 109 patients revealed the existence of similar amounts of progressive forms in different endemic foci, as well as a dependence of such forms on the syndrome of the acute period. It was possible to demonstrate a transformation of progressive syndromes in dynamics. The outcome of syndromes in a progressive development are phenocopies of the known hereditary diseases of the nervous system. The clinical forms of progressive development are determined mainly by hereditary factors. Their appearance is due to an immune defect which facilitates the development of a persisting infection. Hopeful results are provided by specific and nonspecific vaccinotherapy.