Mathematical modelling and release thresholds of transgenic sterile mosquitoes.

We formulate simple differential equation models to study the impact of releases of transgenic sterile mosquitoes carrying a dominant lethal on mosquito control based on the modified sterile insects technique. The early acting bisex, late acting bisex, early acting female-killing, and late acting female-killing lethality strategies are all considered. We determine release thresholds of the transgenic sterile mosquitoes, respectively, for these models by investigating the existence of positive equilibria and their stability. We compare the model dynamics, in particular, the thresholds of the models numerically. The late acting lethality strategies are generally more effective than their corresponding early acting lethality strategies, but the comparison between the late acting bisex and early acting female-killing lethality strategies depends on different parameter settings.