Anticardiolipin antibody in recurrent spontaneous aborting and fertile women.

OBJECTIVE

To determine the association between the presence of anticardiolipin antibody and a history of recurrent spontaneous abortion.

STUDY

DESIGN

Clinical controlled study.

LOCATION: Department of Gynecology and Obstetrics-University of Campinas (UNICAMP).

SUBJECTS: 52 individuals with recurrent spontaneous abortion were included in Group 1 and 104 individuals with at least one live born child in Group 2. Elapsed time from last delivery to blood sampling varied from six months to two years.

METHOD: Between November 1993 and November 1994, patients' blood samples were screened for anticardiolipin antibody by ELISA, as described by Triplett, Barna and Unger (1993).

ANALYSIS: Chi-square and Fisher's Exact tests were used for statistical analysis. Student's "t" test was used to compare the means.

RESULTS

There was no statistical difference in the presence of the anticardiolipin antibody between Group 1 (zero and 2.9%) and Group 2 (7.7 and 5.8%).

CONCLUSION

There was no association between the presence of anticardiolipin antibody and recurrent spontaneous abortion.