The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2013
Preeclampsia is an independent risk factor for spontaneous intestinal perforation in very preterm infants.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Yılmaz Yavuz, Kutman H Gözde Kanmaz, Ulu Hülya Özkan, Canpolat F Emre, Uraş Nurdan, Oğuz S Suna, Dilmen Ugur
Аннотация
BACKGROUND: Spontaneous intestinal perforation (SIP) is an important surgical emergency in preterm infants.
AIMS: To evaluate the effect of maternal preeclampsia on development of SIP in premature infants.
STUDY DESIGN: Retrospective observational study in a large tertiary neonatal intensive care unit.
SUBJECTS: The preterm infants of ≤32 weeks of gestational age and birthweight ≤1500 g who were hospitalized were enrolled.
OUTCOME MEASURES: The primary outcome was to determine the association between preeclampsia and SIP.
RESULTS: A total of 22 infants had SIP diagnosis. The incidence of SIP in infants born to preeclamptic mothers (6.2%) was significantly higher compared with those born to normotensive mothers (0.2%). In multinominal logistic regression model, preeclampsia was found to be an independent risk factor of SIP with an odds ratio of 13.5 (95% confidence interval 2.82-65.1).
CONCLUSIONS: Maternal preeclampsia seemed to be an independent risk factor for development of SIP in premature infants.
AIMS: To evaluate the effect of maternal preeclampsia on development of SIP in premature infants.
STUDY DESIGN: Retrospective observational study in a large tertiary neonatal intensive care unit.
SUBJECTS: The preterm infants of ≤32 weeks of gestational age and birthweight ≤1500 g who were hospitalized were enrolled.
OUTCOME MEASURES: The primary outcome was to determine the association between preeclampsia and SIP.
RESULTS: A total of 22 infants had SIP diagnosis. The incidence of SIP in infants born to preeclamptic mothers (6.2%) was significantly higher compared with those born to normotensive mothers (0.2%). In multinominal logistic regression model, preeclampsia was found to be an independent risk factor of SIP with an odds ratio of 13.5 (95% confidence interval 2.82-65.1).
CONCLUSIONS: Maternal preeclampsia seemed to be an independent risk factor for development of SIP in premature infants.