Journal of clinical anesthesia · 2019
Recent cocaine use and the incidence of hemodynamic events during general anesthesia: A retrospective cohort study.
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Moon Tiffany S, Gonzales Michael X, Sun Joshua J, Kim Agnes, Fox Pamela E, Minhajuddin Abu T, Pak Taylor J, Ogunnaike Babatunde
Аннотация
STUDY OBJECTIVE: To evaluate the intraoperative hemodynamics and medication requirements of cocaine-positive patients compared to matched cocaine-negative controls.
DESIGN: Retrospective cohort study.
SETTING: Public county hospital.
PATIENTS: 821 patients undergoing general anesthesia.
MEASUREMENTS: Incidence of hemodynamic events, defined by a mean arterial pressure of <65 mmHg or >105 mmHg or a heart rate of <50 beats per minute or >100 beats per minute.
MAIN RESULTS: Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
CONCLUSIONS: Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
DESIGN: Retrospective cohort study.
SETTING: Public county hospital.
PATIENTS: 821 patients undergoing general anesthesia.
MEASUREMENTS: Incidence of hemodynamic events, defined by a mean arterial pressure of <65 mmHg or >105 mmHg or a heart rate of <50 beats per minute or >100 beats per minute.
MAIN RESULTS: Cocaine-positive patients did not experience a higher incidence of hemodynamic events when compared with matched cocaine-negative patients. Cocaine-positive patients were not more likely to be administered vasopressors intraoperatively but did receive more anti-hypertensive agents. The minimum alveolar concentration of anesthetics used was similar between the two groups. Anesthesia duration, length of stay, and in-hospital mortality did not significantly differ between the two cohorts.
CONCLUSIONS: Cocaine-positive patients did not demonstrate more intraoperative hemodynamic events or adverse short-term outcomes as compared to matched cocaine-negative controls.
Предметные рубрики MeSH
AdultAnesthesia, GeneralAntihypertensive AgentsArterial PressureCase-Control StudiesCocaineElective Surgical ProceduresFemaleHeart RateHospital MortalityHumansHypertensionHypotensionIncidenceIntraoperative CareLength of StayMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesVasoconstrictor Agents