[Problems concerning metastasis of malignant tumors].

The data on metastases incidence in new discovered patients with malignant tumors of general localizations are presented. The status of current investigations on the ways and mechanisms of metastases, as the basis for elaborating measures of their prevention, is characterized. The most effective methods of diagnosis and treatment of regional and distant metastases are described. Special attention is given to the necessity of using combined and complex treatment of metastatic forms of malignant tumors. It is shown, that along with the widely used methods, the application of radioisotopic, hormonal and some physicochemical influences, hyperthermia and hyperglycemia in particular, seems to be quite promising for this purpose.