Медицинская библиотека · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2002

[The study on the anti-oxidation effect of root of Mallotus apelta in the rat model of liver fibrosis].

Zhao Jinjun, Lü Zhiping, Wang Xiaodong, Zhang Xufu

Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

To investigate the effect of root of Mallotus apelta in treatment of liver fibrosis and the effect of anti-oxidation in the rat model of liver fibrosis.

METHODS

A rat model of liver fibrosis was induced with 40% CCl4 in peanut oil. A series of items were detected, which include ALT, AST, MDA, NO and hydroxyproline in the blood or liver tissues.

RESULTS

The level of ALT, MDA, NO in serum were significantly decreased, the level of hydroxyproline was declined too, while the formation of liver fibrosis was successfully ameliorated.

CONCLUSION

The root of Mallotus apelta could retain the progression of liver fibrosis, having a capacity of anti-oxidation. And the latter might be the reason of the former function.

Для цитирования: Zhao Jinjun, Lü Zhiping, Wang Xiaodong, Zhang Xufu. [The study on the anti-oxidation effect of root of Mallotus apelta in the rat model of liver fibrosis].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2002.

Предметные рубрики MeSH

Animals Antioxidants Carbon Tetrachloride Poisoning Drugs, Chinese Herbal Liver Liver Cirrhosis, Experimental Male Mallotus Plant Plant Roots Plants, Medicinal Rats Rats, Wistar

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