Wei sheng yan jiu = Journal of hygiene research · 2009
[Meta-analysis of the effects on hormone replacement therapy and oral contraceptives associated with female lung cancer risk].
Аннотация на английскомСтатьяМетаанализПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chen Xing, Cai Lin
Аннотация
OBJECTIVE: To evaluate the effects of hormone replacement therapy (HRT) and oral contraceptives (OCs) on lung cancer risk in women.
METHODS: We retrieved studies by systematically searching Medline and other computerized databases. Pooled odds ratios (OR) were appropriately derived from fixed-effects or, in the presence of heterogeneity, random-effects models.
RESULTS: Twelve studies were identified including 3 cohort studies and 9 case-control studies. The OR value associated with HRT was 0.88 (95% CI: 0.77-1.01). Subgroup analyses by smoking revealed that the OR value associated with HRT in smokers' and non-smokers' women were 0.76(95% CI: 0.61-0.95) and 0.78 (95% CI: 0.64-0.95), respectively. There was no statistical relationship between lung cancer risk and OCs (OR = 0.95; 95% CI: 0.83-1.20).
CONCLUSION: The results suggest a potential decreased risk of female lung cancer might be associated with HRT. Additional well-designed studies are warranted to validate these findings.
METHODS: We retrieved studies by systematically searching Medline and other computerized databases. Pooled odds ratios (OR) were appropriately derived from fixed-effects or, in the presence of heterogeneity, random-effects models.
RESULTS: Twelve studies were identified including 3 cohort studies and 9 case-control studies. The OR value associated with HRT was 0.88 (95% CI: 0.77-1.01). Subgroup analyses by smoking revealed that the OR value associated with HRT in smokers' and non-smokers' women were 0.76(95% CI: 0.61-0.95) and 0.78 (95% CI: 0.64-0.95), respectively. There was no statistical relationship between lung cancer risk and OCs (OR = 0.95; 95% CI: 0.83-1.20).
CONCLUSION: The results suggest a potential decreased risk of female lung cancer might be associated with HRT. Additional well-designed studies are warranted to validate these findings.