Emerging infectious diseases · 2004
Endemic Venezuelan equine encephalitis in northern Peru.
СтатьяПоддержка исследования: вне правительства СШАПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Aguilar Patricia V, Greene Ivorlyne P, Coffey Lark L, Medina Gladys, Moncayo Abelardo C, Anishchenko Michael, Ludwig George V, Turell Michael J, O'Guinn Monica L, Lee John, Tesh Robert B, Watts Douglas M, Russell Kevin L, Hice Christine, Yanoviak Stephen, Morrison Amy C, Klein Terry A, Dohm David J, Guzman Hilda, Travassos da Rosa Amelia P A, Guevara Carolina, Kochel Tadeusz, Olson James, Cabezas Cesar, Weaver Scott C
Аннотация
Since Venezuelan equine encephalitis virus (VEEV) was isolated in Peru in 1942, >70 isolates have been obtained from mosquitoes, humans, and sylvatic mammals primarily in the Amazon region. To investigate genetic relationships among the Peru VEEV isolates and between the Peru isolates and other VEEV strains, a fragment of the PE2 gene was amplified and analyzed by single-stranded conformation polymorphism. Representatives of seven genotypes underwent sequencing and phylogenetic analysis. The results identified four VEE complex lineages that cocirculate in the Amazon region: subtypes ID (Panama and Colombia/Venezuela genotypes), IIIC, and a new, proposed subtype IIID, which was isolated from a febrile human, mosquitoes, and spiny rats. Both ID lineages and the IIID subtype are associated with febrile human illness. Most of the subtype ID isolates belonged to the Panama genotype, but the Colombia/Venezuela genotype, which is phylogenetically related to epizootic strains, also continues to circulate in the Amazon basin.