Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2003
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Клиническое исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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UStün Yakup, Erdogan Ozgür, Esen Emin, Karsli Ebru Deniz
Аннотация
OBJECTIVE: The aim of this study was to compare the effects of intravenous administration of 1.5 mg/kg and 3 mg/kg of methylprednisolone sodium succinate (MP) on pain, swelling, and trismus after third molar surgery.
STUDY DESIGN: Twenty-six healthy patients with symmetrically impacted mandibular third molars were included in this double-blind, cross-over study. Either 1.5 mg/kg or 3 mg/kg of MP was administered by intravenous route one hour prior to the first operation. At the second operation the other dose was applied. Trismus was determined by measuring maximum interincisal opening and facial swelling was evaluated using a tape measuring method. Pain was determined using visual analogue scale and recording the number of pain pills taken.
RESULTS: There was no statistically significant difference in trismus, facial swelling, and pain between the two groups.
CONCLUSION: No clinical benefit of the higher dose of MP was demonstrated.
STUDY DESIGN: Twenty-six healthy patients with symmetrically impacted mandibular third molars were included in this double-blind, cross-over study. Either 1.5 mg/kg or 3 mg/kg of MP was administered by intravenous route one hour prior to the first operation. At the second operation the other dose was applied. Trismus was determined by measuring maximum interincisal opening and facial swelling was evaluated using a tape measuring method. Pain was determined using visual analogue scale and recording the number of pain pills taken.
RESULTS: There was no statistically significant difference in trismus, facial swelling, and pain between the two groups.
CONCLUSION: No clinical benefit of the higher dose of MP was demonstrated.
Предметные рубрики MeSH
AcetaminophenAdolescentAdultAnalgesics, Non-NarcoticAnti-Inflammatory AgentsCross-Over StudiesDouble-Blind MethodEdemaFemaleHumansMaleMethylprednisoloneMolar, ThirdPain MeasurementPostoperative PainPostoperative ComplicationsPremedicationProspective StudiesStatistics, NonparametricTooth ExtractionTooth, ImpactedTrismus