JAMA · 1995
Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. Human Fetal Tissue Working Group.
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Branch D W, Ducat L, Fantel A, Low W C, Zhou F C, Dayton D H, Gill T J
Аннотация
OBJECTIVE: To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy.
DESIGN: Tissue collection and analysis by personnel skilled in tissue banking.
SETTING: Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health.
PATIENTS: All women entering obstetric clinics during 1993 who consented to participate in the study.
INTERVENTIONS: None.
MAIN OUTCOME MEASURES: Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria.
RESULTS: From 22,235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy.
CONCLUSION: Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.
DESIGN: Tissue collection and analysis by personnel skilled in tissue banking.
SETTING: Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health.
PATIENTS: All women entering obstetric clinics during 1993 who consented to participate in the study.
INTERVENTIONS: None.
MAIN OUTCOME MEASURES: Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria.
RESULTS: From 22,235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy.
CONCLUSION: Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.