Медицинская библиотека · American journal of obstetrics and gynecology · 2008

Evaluation of mifepristone as a once a month contraceptive pill.

Agarwal Mukta, Das Vinita, Agarwal Anjoo, Pandey Amita, Srivastava Deepali

Клиническое исследованиеСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

The purpose of this study was to assess the efficacy and safety of mifepristone as a contraceptive pill.

STUDY

DESIGN

A prospective case-control study was conducted in a tertiary care center of North India. The study group (n = 86) was given 200-mg mifepristone tablets on the 16th day of the menstrual cycle. The control group (n = 92) received combined oral contraceptive (COC) as per protocol. Subjects were followed for drug compliance, satisfaction, side effects, and failure.

RESULTS

Acceptability of mifepristone was significantly higher in educated population (P < .001), with fewer side effects (P = .001), good satisfaction (P < .001), and higher compliance rate (P = .05). The oral contraceptive pill group had higher adverse biochemical parameters.

CONCLUSION

Mifepristone can be used as a monthly contraceptive pill effectively.

Для цитирования: Agarwal Mukta, Das Vinita, Agarwal Anjoo, Pandey Amita, Srivastava Deepali. Evaluation of mifepristone as a once a month contraceptive pill.. American journal of obstetrics and gynecology. 2008. DOI: 10.1016/j.ajog.2008.09.005.

Предметные рубрики MeSH

Adult Case-Control Studies Contraception Contraceptives, Oral, Synthetic Female Follow-Up Studies Humans India Menstrual Cycle Mifepristone Patient Satisfaction Prospective Studies Young Adult

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