Journal de gynecologie, obstetrique et biologie de la reproduction · 1994
[The value of early morphologic ultrasonography for the detection of chromosome anomalies].
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Petitcolas J, Couvreur A, Leboullenger P, Rossi A
Аннотация
OBJECTIVES: To demonstrate the benefit, in terms of improved antenatal screening, in particular for 21-trisomy, to be expected from the introduction of routine vaginal morphologic echography during the first trimester of pregnancy. This work was conducted by the Department of Gynaecology-Obstetrics of the French Red Cross Teaching Hospital in Bois-Guillaume, France.
SUBJECT: Over a 20 month period, 307 consultating women underwent routine endovaginal echography between the 10th and 13th week of amenorrhoea. The exploration was proposed to detect small retrocervical hydromas as a signal for further cytogenetic tests.
RESULTS: Five hygromas were discovered and led to the diagnosis of 4 cases of 21-trisomy, the fifth pregnancy ended with spontaneous abortion. The 12th week appeared as the most favourable time for routine examination.
CONCLUSIONS: This non-invasive method, routinely performed in all women, improves the yield of screening for 21-trisomy and allows a better means of indicating cytogenetic tests.
SUBJECT: Over a 20 month period, 307 consultating women underwent routine endovaginal echography between the 10th and 13th week of amenorrhoea. The exploration was proposed to detect small retrocervical hydromas as a signal for further cytogenetic tests.
RESULTS: Five hygromas were discovered and led to the diagnosis of 4 cases of 21-trisomy, the fifth pregnancy ended with spontaneous abortion. The 12th week appeared as the most favourable time for routine examination.
CONCLUSIONS: This non-invasive method, routinely performed in all women, improves the yield of screening for 21-trisomy and allows a better means of indicating cytogenetic tests.