[Comparative evaluation of the influence of calcium channel blockers of derivatives of 1,4-dihydropyridine--amlodipine and dimeodipine--on parameters of carbohydrate metabolism in the blood of rats with doxorubicin-induced cardiomyopathy].

Presented are experimental data on the influence of calcium antagonists of the third-generation derivatives of 1,4-dihydropyridines--amlodipine (1.5 mg/kg), dimeodipine (1.5 mg/kg)--on parameters of carbohydrate metabolism in rat blood model doxorubicin-induced cardiomyopathy. The possibility for correcting carbohydrate metabolic disorders in the blood with the above drugs through a reduction of lactate, lactate/pyruvic retio, LDH activity, normalization of the level of glycogen, glucose, pyruvate.