American journal of otolaryngology · 2021
18F-FDG-PET/CT interpretation pitfalls in patients with head and neck cancer.
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Tsetsos Nikolaos, Poutoglidis Alexandros, Arsos Georgios, Tsentemeidou Aikaterini, Kilmpasanis Adamantios, Katsampoukas Dimitrios, Fyrmpas Georgios
Аннотация
AIM: The aim of the present study is to raise awareness of ENT Surgeons on the limitations of 18F-FDG PET/CT in head and neck cancer by presenting illustrative cases from our department archives.
MATERIALS AND METHODS: A retrospective chart review was conducted for all patients with head and neck cancer treated in our ENT department from 2015 to 2020. Cases with various interpretation pitfalls due to false-positive and false-negative PET/CT results that lead to diagnostic dilemmas and treatment delays either in their pre-therapeutic work-up or in their post-therapeutic monitoring were included.
RESULTS: Five cases of various image interpretation pitfalls (3 false negative and 2 false positive cases) were identified and are presented in detail.
CONCLUSIONS: Although 18F-FDG PET/CT has gained in popularity and improved head and neck cancer management, clinicians should be aware of its limitations. The combination of 18F-FDG PET/CT with other imaging modalities can reduce the number of interpretation pitfalls but by no means will substitute sound clinical judgement.
MATERIALS AND METHODS: A retrospective chart review was conducted for all patients with head and neck cancer treated in our ENT department from 2015 to 2020. Cases with various interpretation pitfalls due to false-positive and false-negative PET/CT results that lead to diagnostic dilemmas and treatment delays either in their pre-therapeutic work-up or in their post-therapeutic monitoring were included.
RESULTS: Five cases of various image interpretation pitfalls (3 false negative and 2 false positive cases) were identified and are presented in detail.
CONCLUSIONS: Although 18F-FDG PET/CT has gained in popularity and improved head and neck cancer management, clinicians should be aware of its limitations. The combination of 18F-FDG PET/CT with other imaging modalities can reduce the number of interpretation pitfalls but by no means will substitute sound clinical judgement.
Предметные рубрики MeSH
AdultAgedFalse Negative ReactionsFalse Positive ReactionsFemaleFluorine RadioisotopesFluorodeoxyglucose F18Head and Neck NeoplasmsHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesSensitivity and Specificity