Contraception in hereditary angioedema.

OBJECTIVE

To report a case of successful use of a transdermal contraceptive in a patient with hereditary angioedema.

DESIGN

Case report.

SETTING

University medical center.

PATIENT(S): A patient who had used oral contraceptives contracted SC and submucosal tumefaction every 1 or 2 months. She was diagnosed with type I hereditary angioedema. It was determined that she was complement C4 deficient and C1-inhibitor quantitative deficient but functional C1-inhibitor normal. After she was diagnosed, the use of oral contraceptives was contraindicated.

INTERVENTION(S): Oral contraceptives were suspended, and a hormonal transdermal contraceptive was started.

MAIN OUTCOME MEASURE(S): The absence of symptoms after 26 months using a transdermal contraceptive.

RESULT(S): After 26 months of using this treatment, the patient has not experienced any symptoms of the hereditary angioedema.

CONCLUSION(S): The use of hormonal contraceptives transdermally can be an alternative in patients with hereditary angioedema.