Research and practice in thrombosis and haemostasis · 2024
Apixaban overdose in children: case report and proposed management. A brief communication from the Pediatric and Neonatal Thrombosis and Hemostasis SSC of ISTH.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Wiggins Meredith, Biss Tina, Raffini Leslie, Van Ommen Heleen, Chan Anthony, Vanderpluym Christina, Goldenberg Neil, Monagle Paul
Аннотация
BACKGROUND: Direct oral anticoagulants are commonly prescribed for adults and increasingly also for children requiring anticoagulation therapy. While household medications should not be accessible to children, accidental, and intentional overdoses occur.
KEY CLINICAL QUESTION: How should apixaban overdose in children be managed?.
CLINICAL APPROACH: We present a case of an accidental overdose with the factor Xa antagonist apixaban in a young child and propose an approach to the management of cases of apixaban overdose in children.
CONCLUSION: Given the increasing use of direct oral anticoagulants, it is important to have an approach to the management of overdose of these medications.
KEY CLINICAL QUESTION: How should apixaban overdose in children be managed?.
CLINICAL APPROACH: We present a case of an accidental overdose with the factor Xa antagonist apixaban in a young child and propose an approach to the management of cases of apixaban overdose in children.
CONCLUSION: Given the increasing use of direct oral anticoagulants, it is important to have an approach to the management of overdose of these medications.