Journal of clinical pharmacy and therapeutics · 2015
Is it tinidazole-induced pancreatitis?
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Hegazi M O, Saleh F, John J E
Аннотация
WHAT IS KNOWN AND OBJECTIVE: Metronidazole is one of the drugs with a well-recognized potential to rarely cause acute pancreatitis. The relation of other drugs of the 5-aminoimidazole group (e.g. tinidazole) to acute pancreatitis remains unknown. For the treatment of protozoal infections, tinidazole may be considered as an alternative to metronidazole in cases of intolerability or inadequate response.
CASE SUMMARY: We report a case of acute pancreatitis possibly induced by tinidazole.
WHAT IS NEW AND CONCLUSION: Tinidazole may probably cause acute pancreatitis similar to metronidazole. Physicians may occasionally encounter an individual with history of metronidazole-induced pancreatitis who requires antiprotozoal therapy. We believe it may be safer to choose a drug outside the 5-aminoimidazole group in this situation.
CASE SUMMARY: We report a case of acute pancreatitis possibly induced by tinidazole.
WHAT IS NEW AND CONCLUSION: Tinidazole may probably cause acute pancreatitis similar to metronidazole. Physicians may occasionally encounter an individual with history of metronidazole-induced pancreatitis who requires antiprotozoal therapy. We believe it may be safer to choose a drug outside the 5-aminoimidazole group in this situation.