Ceska gynekologie · 2006
[Hormonal contraception interactions].
Аннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Hurt K, Sottner J, Záhumenský J, Halaska M, Krcmár M, Krajcová A
Аннотация
OBJECTIVE: The purpose of this article is to discuss the probable ways of interactions between some drugs or remedies and steroid contraceptives.
DESIGN: A review article.
SETTING: OBGYN Clinic of the 1t Faculty of Medicine, Prague, Teaching Hospital Bulovka.
SUBJECT: Low dose oral contraceptives are very popular these days. Some drugs and remedies could negatively influence the levels of ethinyl estradiol (EE) and/or progestins and thus increase the possibility of their failure. These drugs mostly implicate as an inducer of the CYP450 system (liver) and as an inducer of P-glycoprotein transport system (transmembrane drug pump in the intestines). We wanted to describe briefly the mechanism and the principles of their impact.
DESIGN: A review article.
SETTING: OBGYN Clinic of the 1t Faculty of Medicine, Prague, Teaching Hospital Bulovka.
SUBJECT: Low dose oral contraceptives are very popular these days. Some drugs and remedies could negatively influence the levels of ethinyl estradiol (EE) and/or progestins and thus increase the possibility of their failure. These drugs mostly implicate as an inducer of the CYP450 system (liver) and as an inducer of P-glycoprotein transport system (transmembrane drug pump in the intestines). We wanted to describe briefly the mechanism and the principles of their impact.