American journal of rhinology · 2006
Does the use of the combined oral contraceptive pill cause changes in the nasal physiology in young women?
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Wolstenholme Charlotte R, Philpott Carl M, Oloto Emeka J, Murty George E
Аннотация
BACKGROUND: Changes in nasal physiology have been observed during pregnancy and the menstrual cycle. The role of female hormones in these changes is unclear. The aim is to investigate the effect of the modern combined oral contraceptive pill (COCP).
METHODS: Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
RESULTS: Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
CONCLUSION: The modern COCP has no significant effect on nasal physiology.
METHODS: Eleven women were recruited from a family planning clinic. Anterior rhinoscopy, peak inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time, and rhinitis quality-of-life questionnaire (RQLQ) scores were recorded at days 1 and 14 pre- and post-COCP.
RESULTS: Increased nasal obstruction midcycle pre-COCP, with significant differences for anterior rhinoscopy (p = 0.001) and peak inspiratory flow rate (p = 0.022), was found. No statistical difference was shown between pre- and post-COCP results apart from day 1 anterior rhinoscopy findings (p = 0.05).
CONCLUSION: The modern COCP has no significant effect on nasal physiology.
Предметные рубрики MeSH
Administration, IntranasalAdolescentAdultAirway ResistanceContraceptives, Oral, CombinedFemaleHumansInspiratory CapacityMucociliary ClearanceNasal MucosaNasal ObstructionNosePulmonary VentilationQuality of LifeRhinitisRhinomanometryRhinometry, AcousticSurveys and QuestionnairesTime FactorsTurbinates