[Cerebral blood flow (measured by means of isotopes) and base-acid-equilibrium of the CSF in migraine (author's transl)].

In migraine patients a considerable metabolic disturbance characterised by a decrease in bicarbonate and in increase in lactate was demonstrated during the migrainous status. Measurements of the cerebral circulation were taken by means of radioactive isotopes and showed a distinct decrease in blood supply to the entire brain during the migraine attack. Following forced hyperventilation during the attack-free interval a pathological reactivity with decreased blood flow was found in the hemisphere which had been indicated as the usual site of the migrainous pain.