[In vitro effects of L-carnitine on the inhibition of sperm mobility induced by FANS].

OBJECTIVE

We wanted to study the function of some substances present in the seminal fluid (PG and L. Carnitine), which, with different mechanisms, affected Spermatozoa motility, and to study the effect of other substances (F.A.N.S.), known also for their action on P.G.

PATIENTS AND

METHODS

Ten samples of seminal fluid from healthy subjects were studied according to the indications of the World Health Organization (1992).

RESULTS

All the F.A.N.S. used (Cinnoxicam, Salicylic Acetyl Acid) had an inhibitory effect on motility, as did L. Carnitine at high doses. We thought it interesting to observe if L. Carnitine added to the seminal fluid before F.A.N.S. blocked their effects.

CONCLUSIONS

The pre-treatment with L. Carnitine had an "in vitro" buffering effect on F.A.N.S.