[Effect of sulfur dioxide on surface activity of the pulmonary surfactants and ultrastructure of type II alveolocytes].

Condition of the surfactant lungs system under sulfur dioxide action in concentration of 0.05 mg/m3 and 0.5 mg/m3 was studied in dynamics (1 hour, 24 hours, 7 days) during the investigation of 108 white rat-males with the help of electronic-microscopic and physic methods. We established that sulfur dioxide decreases the surface activity of the lungs surfactant, damages the ultrastructure of II type of alveolocytes. The greatest changes of the surfactant lung system were induced by inhalation of sulfur dioxide in concentration of 0.5 mg/m3.