A 22-month-old girl with lesions on the face and extremities.

CME EDUCATIONAL OBJECTIVES: 1.Diagnose Gianotti-Crosti syndrome (GCS) based on the clinical presentation.2.Understand the various etiologies (viral, immunizations, bacterial) associated with GCS.3.Know the natural course of GCS. A 22-month-old black girl presented to the emergency department with a 5-day history of an itchy rash. Her family reported that the rash started as itchy bumps on the extremities and spread to the face and buttocks and was associated with a runny nose and cough. There was no history of fevers, abdominal pain, vomiting or diarrhea. The patient had a medical history significant for pyleonephritis, pneumonia, and meningitis. She did not have any allergies to medications and was not taking any medications.