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Anais brasileiros de dermatologia · 2017

Investigation of Demodex folliculorum frequency in patients with polycystic ovary syndrome.

СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Eser Ayla, Erpolat Seval, Kaygusuz Ikbal, Balci Hatice, Kosus Aydin

Аннотация

BACKGROUND: Background: Demodex mites are acari that reside in the pilosebaceous unit of the skin and have been associated with skin disorders.

OBJECTIVE: The objective of this study was to investigate the prevalence of Demodex folliculorum (D. folliculorum) mites in polycystic ovary syndrome patients as well as to examine the relationship between Demodex infestation and the presence of acne and oily or dry skin types in polycystic ovary syndrome patients.

METHODS: 41 polycystic ovary syndrome patients and 47 non-polycystic ovary syndrome control subjects were enrolled in the study. polycystic ovary syndrome was diagnosed according to the revised 2003 ESHRE/ASRM polycystic ovary syndrome Consensus Workshop Group diagnostic criteria. Microscopic examination of D. folliculorum mites was carried out by standardized skin surface biopsy. The result was considered positive when there were more than 5 mites per cm2.

RESULTS: D. folliculorum was positive in 53.7% of the polycystic ovary syndrome patients and 31.9% of the non-polycystic ovary syndrome group (p=0.052). Demodex positivity was significantly associated with acne (p=0.003) and oily skin (p=0.005) in the polycystic ovary syndrome patients but not in the controls.

STUDY LIMITATION: Our study is limited by the relatively small number of subjects and the observational nature of the study design.

CONCLUSION: Demodex mites might have a role in acne pathogenesis in patients with polycystic ovary syndrome. Anti-Demodex treatment may increase the response to treatment of acne. Further studies are indicated.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты