[Experience and comparison of antihypertensive effect of ace inhibitor spirapril and calcium antagonist amlodipinein standard and chronotherapeutic prescription mode].

Arterial pressure is an effect of many physiologic processes of organism effected by daily rhytmus. The introduction of round the 24-hour monitoring of arterial pressure enabled to detect arterial pressure circular fluctuation. Chronotherapy with the application of amlodipin and spirapril due to the data of round the 24-hour arterial pressure monitoring increases the effectiveness of antihypertensive therapy.