[Mechanisms of biocidal action of neutrophils in patients with alcoholism and kidney damage of the chronic pyelonephritis type].

AIM: To study mechanisms of biocenosis action of neutrophils in alcoholics with chronic pyelonephritis (CP).

MATERIAL AND

METHODS

Functional potential of oxidase neutrophil system was studied in 37 males with chronic alcoholism stage II. 17 of them had CP. They were compared to 18 CP non-alcohol abusers (controls).

RESULTS

CP alcoholics had lower potential of oxidase neutrophil system than controls and healthy subjects.

CONCLUSION

Dysfunction of axygen-dependent mechanisms of biocidic action of neutrophils in chronic alcoholics weakens the ability of the organism to eliminate infection and can entail defects in immune response.