[Chemical Constituents of Salvia grandifolia].

OBJECTIVE

To study the chemical constituents of Salvia grandifolia.

METHODS

The chemical constituents were isolated and purified by means of chromatographic techniques and their structures were elucidated by spectroscopic methods.

RESULTS

Eleven compounds were isolated from chloroform and ethyl acetate of ethanol extract, and identified as tanshinone Ⅵ( 1),tetrahydrotanshiquinone( 2),tanshinone ⅡB( 3),danshenol B( 4), ursolic acid( 5),2α-hydroxyursolic acid( 6),2α,3α-dihydroxyurs-12-en-28-oic acid( 7),salvianolic acid B(8),3,5-dihydroxycinnamic acid( 9),ethyl 3-( 3,4-dihydrophenyl) lactate( 10) and nepetoidin B( 11).

CONCLUSION

All of them are isolated from this plant for the first time.