A literature survey of the potentially adverse effects of the drugs commonly prescribed for the elderly.

Part I: Hard data concerning adverse drug reactions are notoriously difficult to obtain. Some of the problems arise because of: --patient variables including age, sex, genetic differences, and current illness. --multiple drug use, continuation of smoking, and use of alcohol. --variations in dose, duration of treatment, and route of administration. --some effects are not reported but many reported effects are not truly due to the drug indicated. Nevertheless, we need to be aware of potential adverse reactions. Our ability to recognize drug side effects will be improved if we have some idea which kinds of reaction may occur. Part I deals with the analgesics, sedatives, laxatives, antacids, antidiabetic agents, antihypertensives and cardiovascular drugs. Potential systemic and ocular adverse reactions are listed.