Recent Research Advances in Multi-Functional Diallyl Trisulfide (DATS): A Comprehensive Review of Characteristics, Metabolism, Pharmacodynamics, Applications, and Drug Delivery Systems.

Diallyl trisulfide (DATS) is an organic sulfur compound derived from garlic (Allium sativum L). DATS is characterized by its oily and volatile nature, exhibiting insolubility in water and ethanol, while being miscible with ether. This property enhances its extraction process and expands its applicability across various fields. Recent studies have elucidated the diverse effects of DATS, demonstrating significant progress in healthcare, the food industry, and nanoformulation research. Research on DATS is currently limited, hindering a comprehensive understanding and appreciation of its possibilities for future development. This review offers an in-depth examination of the characteristics of DATS, highlighting the significant advancements and benefits achieved in the fields of drug metabolism, pharmacological effects, clinical trials, food chemistry applications, and nanoformulation research over the past two decades. In addition, this review examines the future prospects of DATS, emphasizing its current development status and challenges, while serving as a crucial reference for advancing research, application, and innovation in the field.