Genetics in medicine : official journal of the American College of Medical Genetics · 2003
Effects of pregnancy on the renal and pulmonary manifestations in women with tuberous sclerosis complex.
СтатьяПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mitchell Anna L, Parisi Melissa A, Sybert Virginia P
Аннотация
PURPOSE: To determine whether pregnancy increases the risk of renal or pulmonary complications in women with tuberous sclerosis complex (TSC).
METHODS: We surveyed female members of the Tuberous Sclerosis Alliance and reviewed the files of adult women seen in our genetics clinics for complications of TSC.
RESULTS: Among 145 individuals, there was no significant difference in incidence of renal and pulmonary involvement between the pregnant and never-pregnant groups, although there were differences in age at diagnosis (25 vs. 16) and current age (41 vs. 35). There was no significant difference in the rate of renal complications (57% vs. 67%, P = 0.62) or pneumothorax (40% vs. 38%, P = 1.00) for the pregnant and never-pregnant groups, respectively. Pregnancy loss in women with TSC did not differ from population risks.
CONCLUSIONS: Pregnancy does not increase the risk of developing renal or pulmonary complications in women with TSC.
METHODS: We surveyed female members of the Tuberous Sclerosis Alliance and reviewed the files of adult women seen in our genetics clinics for complications of TSC.
RESULTS: Among 145 individuals, there was no significant difference in incidence of renal and pulmonary involvement between the pregnant and never-pregnant groups, although there were differences in age at diagnosis (25 vs. 16) and current age (41 vs. 35). There was no significant difference in the rate of renal complications (57% vs. 67%, P = 0.62) or pneumothorax (40% vs. 38%, P = 1.00) for the pregnant and never-pregnant groups, respectively. Pregnancy loss in women with TSC did not differ from population risks.
CONCLUSIONS: Pregnancy does not increase the risk of developing renal or pulmonary complications in women with TSC.