Age and ageing · 2013
Sensorimotor and psychosocial determinants of 3-year incident mobility disability in middle-aged and older adults.
СтатьяПоддержка NIH: внешняя программаResearch Support, N.I.H., IntramuralПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Deshpande Nandini, Metter Jeffrey E, Guralnik Jack, Bandinelli Stefania, Ferrucci Luigi
Аннотация
OBJECTIVE: to identify sensorimotor and psychosocial determinants of 3-year incident mobility disability.
DESIGN: prospective.
SETTING: population-based sample of community-dwelling older persons.
PARTICIPANTS: community-living middle-aged and older persons (age: 50-85 years) without baseline mobility disability (n = 622).
MEASUREMENTS: mobility disability, defined as self-reported inability to walk a quarter mile without resting or inability to walk up a flight of stairs unsupported, was ascertained at baseline and 3-year follow-up. Potential baseline determinant characteristics included demographics, education, social support, financial condition, knee extensor strength, visual contrast sensitivity, cognition, depression, presence of chronic conditions and history of falls.
RESULTS: a total of 13.5% participant reported 3-year incident mobility disability. Age ≥75 years, female sex, knee extensor strength in the lowest quartile, visual contrast sensitivity <1.7 on the Pelli-Robson chart or significant depressive symptoms (CESD score >16) were independent determinants of 3-year incident mobility disability (ORs 1.84-16.51).
CONCLUSIONS: low visual contrast sensitivity, poor knee extensor strength and significant depressive symptoms are independent determinants of future onset of mobility disability.
DESIGN: prospective.
SETTING: population-based sample of community-dwelling older persons.
PARTICIPANTS: community-living middle-aged and older persons (age: 50-85 years) without baseline mobility disability (n = 622).
MEASUREMENTS: mobility disability, defined as self-reported inability to walk a quarter mile without resting or inability to walk up a flight of stairs unsupported, was ascertained at baseline and 3-year follow-up. Potential baseline determinant characteristics included demographics, education, social support, financial condition, knee extensor strength, visual contrast sensitivity, cognition, depression, presence of chronic conditions and history of falls.
RESULTS: a total of 13.5% participant reported 3-year incident mobility disability. Age ≥75 years, female sex, knee extensor strength in the lowest quartile, visual contrast sensitivity <1.7 on the Pelli-Robson chart or significant depressive symptoms (CESD score >16) were independent determinants of 3-year incident mobility disability (ORs 1.84-16.51).
CONCLUSIONS: low visual contrast sensitivity, poor knee extensor strength and significant depressive symptoms are independent determinants of future onset of mobility disability.
Предметные рубрики MeSH
Age FactorsAgedAged, 80 and overAgingCognitionContrast SensitivityDependent AmbulationDepressionDisability EvaluationFemaleFinancing, PersonalHumansItalyKneeMaleMiddle AgedMobility LimitationMuscle StrengthMuscle, SkeletalOdds RatioProspective StudiesRisk FactorsSex FactorsSocial SupportTime FactorsWalking