[Effect of temporary hypovolemia on the early central pooling of the blood circulation following resuscitation and the survival of animals experiencing clinical death].

The experiments were conducted on cats under pentobarbitone sodium anesthesia (40 mg/kg). The effect of 30-min hypovolemia (Wiggerse's model, 13.3 kPa or 100 mm Hg) on the cardiac output, its main fractions and the survival of animals recovered after clinical death (5 min) were studied. Hypovolemia was induced after cardiac contractions were recovered. In experimental (19 cats) and control (23 cats) studies clinical death was caused by arterial blood loss. The animals had been previously subject to hemorrhagic hypotension (according to Wiggerse, 6.7 kPa or 50 mm Hg, for 30 minutes). Temporary exclusion of part of blood volume from the circulation was found to abolish the phase of cardiac output increase in the postresuscitation period, attenuate the reaction of blood circulation centralization, improve the course of reparative processes and increase the survival of animals recovered after clinical death.